Enhanced Interleukin-1 Activity Contributes to Exercise Intolerance in Patients with Systolic Heart Failure

BACKGROUND: Heart failure (HF) is a complex clinical syndrome characterized by impaired cardiac function and poor exercise tolerance. Enhanced inflammation is associated with worsening outcomes in HF patients and may play a direct role in disease progression. Interleukin-1β (IL-1β) is a pro-inflamma...

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Autors principals: Van Tassell, Benjamin W., Arena, Ross A., Toldo, Stefano, Mezzaroma, Eleonora, Azam, Tania, Seropian, Ignacio M., Shah, Keyur, Canada, Justin, Voelkel, Norbert F., Dinarello, Charles A., Abbate, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306393/
https://ncbi.nlm.nih.gov/pubmed/22438931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033438
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