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Inhibition of ERβ Induces Resistance to Cisplatin by Enhancing Rad51–Mediated DNA Repair in Human Medulloblastoma Cell Lines

Cisplatin is one of the most widely used and effective anticancer drugs against solid tumors including cerebellar tumor of the childhood, Medulloblastoma. However, cancer cells often develop resistance to cisplatin, which limits therapeutic effectiveness of this otherwise effective genotoxic drug. I...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wilk, Anna, Waligorska, Agnieszka, Waligorski, Piotr, Ochoa, Augusto, Reiss, Krzysztof
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306313/
https://ncbi.nlm.nih.gov/pubmed/22439007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033867
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