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Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts

MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression in post-transcriptional fashion, and emerging studies support their importance in regulating many biological processes, including myogenic differentiation and muscle development. miR-29 is a promoting factor during myogenesis but i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Liang, Wang, Lijun, Lu, Leina, Jiang, Peiyong, Sun, Hao, Wang, Huating
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306299/
https://ncbi.nlm.nih.gov/pubmed/22438993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033766
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