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Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins

Over the past two decades, potent and selective analgesics have been developed from endogenous opioid peptides. Glycosylation provides an important means of modulating interaction with biological membranes, which greatly affects the pharmacodynamics and pharmacokinetics of the resulting glycopeptide...

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Autores principales: Li, Yingxue, Lefever, Mark R, Muthu, Dhanasekaran, Bidlack, Jean M, Bilsky, Edward J, Polt, Robin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306179/
https://ncbi.nlm.nih.gov/pubmed/22300099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.195
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