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Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins

Over the past two decades, potent and selective analgesics have been developed from endogenous opioid peptides. Glycosylation provides an important means of modulating interaction with biological membranes, which greatly affects the pharmacodynamics and pharmacokinetics of the resulting glycopeptide...

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Detalhes bibliográficos
Main Authors: Li, Yingxue, Lefever, Mark R, Muthu, Dhanasekaran, Bidlack, Jean M, Bilsky, Edward J, Polt, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306179/
https://ncbi.nlm.nih.gov/pubmed/22300099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.195
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