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Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins
Over the past two decades, potent and selective analgesics have been developed from endogenous opioid peptides. Glycosylation provides an important means of modulating interaction with biological membranes, which greatly affects the pharmacodynamics and pharmacokinetics of the resulting glycopeptide...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306179/ https://ncbi.nlm.nih.gov/pubmed/22300099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.195 |
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