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Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins

Over the past two decades, potent and selective analgesics have been developed from endogenous opioid peptides. Glycosylation provides an important means of modulating interaction with biological membranes, which greatly affects the pharmacodynamics and pharmacokinetics of the resulting glycopeptide...

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Autors principals: Li, Yingxue, Lefever, Mark R, Muthu, Dhanasekaran, Bidlack, Jean M, Bilsky, Edward J, Polt, Robin
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306179/
https://ncbi.nlm.nih.gov/pubmed/22300099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.195
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