Oral Cyclophosphamide Therapy Diminishes Ovarian Reserve in Women with Granulomatosis with Polyangiitis

OBJECTIVE: Standard treatment for severe granulomatosis with polyangiitis (GPA, previously Wegener’s granulomatosis) is daily oral cyclophosphamide (CYC), a cytotoxic agent associated with ovarian failure. In this study we assessed the rate of diminished ovarian reserve in women with GPA who receive...

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Autores principales: Clowse, Megan E. B., Copland, Susannah C., Hsieh, Tsung-Cheng, Chow, Shein-Chung, Hoffman, Gary S, Merkel, Peter A, Spiera, Robert F, Davis, John C., McCune, W. Joseph, Ytterberg, Steven R., St. Clair, E. William, Allen, Nancy B., Specks, Ulrich, Stone, John H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306000/
https://ncbi.nlm.nih.gov/pubmed/22127969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acr.20605
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