Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis

BACKGROUND: Baseline expression of FCRL5, a marker of naive and memory B cells, was shown to predict response to rituximab (RTX) in rheumatoid arthritis. This study investigated baseline expression of FCRL5 as a potential biomarker of clinical response to RTX in granulomatosis with polyangiitis (GPA...

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Publicado en:JCI Insight
Main Authors: Owczarczyk, Kasia, Cascino, Matthew D., Holweg, Cecile, Tew, Gaik W., Ortmann, Ward, Behrens, Timothy, Schindler, Thomas, Langford, Carol A., St. Clair, E. William, Merkel, Peter A., Spiera, Robert, Seo, Philip, Kallenberg, Cees G.M., Specks, Ulrich, Lim, Noha, Stone, John, Brunetta, Paul, Prunotto, Marco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526555/
https://ncbi.nlm.nih.gov/pubmed/32841219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136180
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