Fc receptor-like 5 and anti-CD20 treatment response in granulomatosis with polyangiitis and microscopic polyangiitis

BACKGROUND: Baseline expression of FCRL5, a marker of naive and memory B cells, was shown to predict response to rituximab (RTX) in rheumatoid arthritis. This study investigated baseline expression of FCRL5 as a potential biomarker of clinical response to RTX in granulomatosis with polyangiitis (GPA...

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Vydáno v:JCI Insight
Hlavní autoři: Owczarczyk, Kasia, Cascino, Matthew D., Holweg, Cecile, Tew, Gaik W., Ortmann, Ward, Behrens, Timothy, Schindler, Thomas, Langford, Carol A., St. Clair, E. William, Merkel, Peter A., Spiera, Robert, Seo, Philip, Kallenberg, Cees G.M., Specks, Ulrich, Lim, Noha, Stone, John, Brunetta, Paul, Prunotto, Marco
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Clinical Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526555/
https://ncbi.nlm.nih.gov/pubmed/32841219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136180
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