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AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells
The gene expression networks governing embryonic stem cell (ESC) pluripotency are complex and finely regulated during differentiation toward specific lineages. We describe a new role for Amd1 (adenosyl methionine decarboxylase), a key enzyme in the polyamine synthesis pathway, in regulating both ESC...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305984/ https://ncbi.nlm.nih.gov/pubmed/22391449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.182998.111 |
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