The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.

The properties of antisense phosphorothioate and unmodified oligodeoxynucleotides have been studied in Xenopus oocytes and embryos. We find that phosphorothioates, like unmodified oligodeoxynucleotides, can degrade Vg1 mRNA in oocytes via an endogenous RNase H-like activity. In oocytes, phosphorothi...

Ful tanımlama

Detaylı Bibliyografya

Yayımlandı:	Nucleic Acids Res
Asıl Yazarlar:	Woolf, T M, Jennings, C G, Rebagliati, M, Melton, D A
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Oxford University Press 1990
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1692405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.7.1763
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!