Targeting the Oxidative Stress Response System of Fungi with Redox-Potent Chemosensitizing Agents

The cellular antioxidant system is a target in the antifungal action of amphotericin B (AMB) and itraconazole (ITZ), in filamentous fungi. The sakAΔ mutant of Aspergillus fumigatus, a mitogen-activated protein kinase (MAPK) gene deletion mutant in the antioxidant system, was found to be more sensiti...

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Bibliografische gegevens
Hoofdauteurs: Kim, Jong H., Chan, Kathleen L., Faria, Natália C. G., Martins, M. de L., Campbell, Bruce C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Research Foundation 2012
Onderwerpen:
Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305922/
https://ncbi.nlm.nih.gov/pubmed/22438852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00088
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