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Targeting the Oxidative Stress Response System of Fungi with Redox-Potent Chemosensitizing Agents
The cellular antioxidant system is a target in the antifungal action of amphotericin B (AMB) and itraconazole (ITZ), in filamentous fungi. The sakAΔ mutant of Aspergillus fumigatus, a mitogen-activated protein kinase (MAPK) gene deletion mutant in the antioxidant system, was found to be more sensiti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305922/ https://ncbi.nlm.nih.gov/pubmed/22438852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00088 |
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