CXCR7 antagonism prevents axonal injury during experimental autoimmune encephalomyelitis as revealed by in vivo axial diffusivity

BACKGROUND: Multiple Sclerosis (MS) is characterized by the pathological trafficking of leukocytes into the central nervous system (CNS). Using the murine MS model, experimental autoimmune encephalomyelitis (EAE), we previously demonstrated that antagonism of the chemokine receptor CXCR7 blocks endo...

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Bibliografske podrobnosti
Main Authors: Cruz-Orengo, Lillian, Chen, Ying-Jr, Kim, Joong Hee, Dorsey, Denise, Song, Sheng-Kwei, Klein, Robyn S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305694/
https://ncbi.nlm.nih.gov/pubmed/22145790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-170
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