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Reproducibility and intraindividual variation over days in buccal cell DNA methylation of two asthma genes, interferon γ (IFNγ) and inducible nitric oxide synthase (iNOS)

The biological mechanisms responsible for the onset and exacerbation of asthma symptoms in children may involve the epigenetic regulation of inflammatory genes after environmental exposures. Using buccal cells, we hypothesized that DNA methylation in promoter regions of two asthma genes, inducible n...

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Detalhes bibliográficos
Main Authors: Torrone, DZ, Kuriakose, JS, Moors, K, Jiang, H, Niedzwiecki, MM, Perera, FF, Miller, RL
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305380/
https://ncbi.nlm.nih.gov/pubmed/22414378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-3
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