Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias

BACKGROUND: High-density genotyping arrays that measure hybridization of genomic DNA fragments to allele-specific oligonucleotide probes are widely used to genotype single nucleotide polymorphisms (SNPs) in genetic studies, including human genome-wide association studies. Hybridization intensities a...

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Detaylı Bibliyografya
Asıl Yazarlar: Didion, John P, Yang, Hyuna, Sheppard, Keith, Fu, Chen-Ping, McMillan, Leonard, de Villena, Fernando Pardo-Manuel, Churchill, Gary A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Methodology Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305361/
https://ncbi.nlm.nih.gov/pubmed/22260749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-34
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