APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage

BACKGROUND: The spindle assembly checkpoint (SAC) inhibits anaphase progression in the presence of insufficient kinetochore-microtubule attachments, but cells can eventually override mitotic arrest by a process known as mitotic slippage or adaptation. This is a problem for cancer chemotherapy using...

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Autors principals: Toda, Kazuhiro, Naito, Kayoko, Mase, Satoru, Ueno, Masaru, Uritani, Masahiro, Yamamoto, Ayumu, Ushimaru, Takashi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305350/
https://ncbi.nlm.nih.gov/pubmed/22321970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-7-4
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