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APC/C-Cdh1-dependent anaphase and telophase progression during mitotic slippage
BACKGROUND: The spindle assembly checkpoint (SAC) inhibits anaphase progression in the presence of insufficient kinetochore-microtubule attachments, but cells can eventually override mitotic arrest by a process known as mitotic slippage or adaptation. This is a problem for cancer chemotherapy using...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3305350/ https://ncbi.nlm.nih.gov/pubmed/22321970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-7-4 |
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