Modulation of glutathione peroxidase expression by selenium: effect on human MCF-7 breast cancer cell transfectants expressing a cellular glutathione peroxidase cDNA and doxorubicin-resistant MCF-7 cells.

We have studied the effect of selenium on the expression of a cellular glutathione peroxidase, GSHPx-1, in transfected MCF-7 cells and in doxorubicin-resistant (Adrr) MCF-7 cells. A GSHPx-1 cDNA with a Rous Sarcoma virus promoter was transfected into a human mammary carcinoma cell line, MCF-7, which...

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Bibliographic Details
Main Authors: Chu, F F, Esworthy, R S, Akman, S, Doroshow, J H
Format: Artigo
Language:Inglês
Published: 1990
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC330522/
https://ncbi.nlm.nih.gov/pubmed/2158080
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