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Suppression of the negative effect of minor arginine codons on gene expression; preferential usage of minor codons within the first 25 codons of the Escherichia coli genes.

AGA and AGG codons for arginine are the least used codons in Escherichia coli, which are encoded by a rare tRNA, the product of the dnaY gene. We examined the positions of arginine residues encoded by AGA/AGG codons in 678 E. coli proteins. It was found that AGA/AGG codons appear much more frequentl...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Chen, G F, Inouye, M
Format: Artigo
Language:Inglês
Published: Oxford University Press 1990
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330513/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2109307/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.6.1465
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