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EM-Fold: De novo atomic-detail protein structure determination from medium resolution density maps

Electron density maps of membrane proteins or large macromolecular complexes are frequently only determined at medium resolution between 4 Å and 10 Å, either by cryo-electron microscopy (cryoEM) or X-ray crystallography. In these density maps the general arrangement of secondary structure elements i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lindert, Steffen, Alexander, Nathan, Wötzel, Nils, Karakaş, Mert, Stewart, Phoebe L., Meiler, Jens
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304577/
https://ncbi.nlm.nih.gov/pubmed/22405005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.01.023
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