Troglitazone Induces Extracellular Matrix and Cytoskeleton Remodeling in Mouse Collecting Duct Cells

Peroxisome proliferator-activated receptor (PPARγ) has been shown to have a protective role in the nephron through its ability to inhibit a transforming growth factor- (TGF-β) mediated fibrotic response. In contrast, PPARγ was also shown to induce a mesenchymal transformation in epithelial intestina...

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Main Authors: Corinaldi, Jaime, Nasrallah, Rania, Clark, Jordan, Paris, Geneviève, Miura, Pedro, Jasmin, Bernard J., Hébert, Richard L.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304576/
https://ncbi.nlm.nih.gov/pubmed/22500093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/507057
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