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Epigenetics, epidemiology and mitochondrial DNA diseases

Over the last two decades, the mutation of mitochondrial DNA (mtDNA) has emerged as a major cause of inherited human disease. The disorders present clinically in at least 1 in 10 000 adults, but pathogenic mutations are found in approximately 1 in 200 of the background population. Mitochondrial DNA...

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Autors principals: Chinnery, Patrick F, Elliott, Hannah R, Hudson, Gavin, Samuels, David C, Relton, Caroline L
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304530/
https://ncbi.nlm.nih.gov/pubmed/22287136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyr232
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