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NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic β-cells

Nitric oxide (NO) has been implicated in pancreatic β-cell death in the development of diabetes. The mechanisms underlying NO-induced β-cell death have not been clearly defined. Recently, receptor-interacting protein-1 (RIP1)-dependent necrosis, which is inhibited by necrostatin-1, an inhibitor of R...

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Detalhes bibliográficos
Main Authors: Tamura, Yoshiaki, Chiba, Yuko, Tanioka, Toshihiro, Shimizu, Nobuyuki, Shinozaki, Shohei, Yamada, Marina, Kaneki, Kentaro, Mori, Seijiro, Araki, Atsushi, Ito, Hideki, Kaneki, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304503/
https://ncbi.nlm.nih.gov/pubmed/21888904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.08.028
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