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The basis of distinctive IL-2- and IL-15-dependent signaling: Weak CD122-dependent signaling favors CD8(+) T(CM) survival but not T(EM) development
Recent work suggests that IL-2 and IL-15 induce distinctive levels of signaling through common receptor subunits and that such varied signaling directs the fate of antigen-activated CD8(+) T cells. Here we directly examined proximal signaling by IL-2 and IL-15 and CD8(+) T cell primary and memory re...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3304468/ https://ncbi.nlm.nih.gov/pubmed/21984699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003961 |
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