Prognostic significance of chromosome 3 alterations determined by microsatellite analysis in uveal melanoma: a long-term follow-up study

BACKGROUND: In uveal melanoma (UM), the most frequent primary intraocular tumour in adults, loss of one entire chromosome 3 (monosomy 3 (M3)) is observed in ∼50% of tumours and is significantly associated with metastatic disease. The strong association of metastatic disease with M3 offers the opport...

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Detalhes bibliográficos
Main Authors: Thomas, S, Pütter, C, Weber, S, Bornfeld, N, Lohmann, D R, Zeschnigk, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304422/
https://ncbi.nlm.nih.gov/pubmed/22353812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.54
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