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Mutation of the histidin residue of the DRH motif in vasopressin V2 receptor expression and function

BACKGROUND AND THE PURPOSE OF THE STUDY: Vasopressin type 2 receptor (V2R), a G protein coupled receptor (GPCR), plays an important role in the regulation of renal antidiuretic function. The highly conserved DRH motif is essential for G protein signaling of V2R; however its role especially regarding...

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Autors principals: Mir Mohammad Sadeghi, H., Rabbani, M., Jafarian, A., Najafzadeh, H., Safaeian, L.
Format: Artigo
Idioma:Inglês
Publicat: Tehran University of Medical Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304347/
https://ncbi.nlm.nih.gov/pubmed/22615630
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