The Effect of Aspartate-Lysine-Isoleucine and Aspartate-Arginine-Tyrosine Mutations on the Expression and Activity of Vasopressin V2 Receptor Gene

Background: Vasopressin type 2 receptor (V2R) plays an important role in the water reabsorption in the kidney collecting ducts. V2R is a G protein coupled receptor (GPCR) and the triplet of amino acids aspartate-arginine-histidine (DRH) in this receptor might significantly influence its activity sim...

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Autores principales: Najafzadeh, Hossein, Safaeian, Leila, Mirmohammad Sadeghi, Hamid, Rabbani, Mohammad, Jafarian, Abbas
Formato: Artigo
Lenguaje:Inglês
Publicado: Pasteur Institute of Iran 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878142/
https://ncbi.nlm.nih.gov/pubmed/20683494
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