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Sequence-dependent structural variations of hammerhead RNA enzymes.
The discovery of in vivo catalytic activity for the hammerhead RNA self-cleaving domain has led to the development of a new class of sequence-specific RNA endonucleases. Two such ribozymes have been synthesized using in vitro transcription with T7 polymerase and their structures have been studied by...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1990
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330421/ https://ncbi.nlm.nih.gov/pubmed/2181399 |
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