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Sequence-dependent structural variations of hammerhead RNA enzymes.

The discovery of in vivo catalytic activity for the hammerhead RNA self-cleaving domain has led to the development of a new class of sequence-specific RNA endonucleases. Two such ribozymes have been synthesized using in vitro transcription with T7 polymerase and their structures have been studied by...

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Autori principali: Heus, H A, Uhlenbeck, O C, Pardi, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC330421/
https://ncbi.nlm.nih.gov/pubmed/2181399
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