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Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging

[Image: see text] Mutually orthogonal tetrazine–transcyclooctene and azide–cyclooctyne cycloaddition reactions were used simultaneously for the bioorthogonal labeling of two different live cell populations in the same culture. These small-molecule probes show good chemical reactivity and can be read...

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Autors principals: Karver, Mark R., Weissleder, Ralph, Hilderbrand, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304098/
https://ncbi.nlm.nih.gov/pubmed/22162316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201104389
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