Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift

This paper describes a new program SnpSift for filtering differential DNA sequence variants between two or more experimental genomes after genotoxic chemical exposure. Here, we illustrate how SnpSift can be used to identify candidate phenotype-relevant variants including single nucleotide polymorphi...

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Autori principali: Cingolani, Pablo, Patel, Viral M., Coon, Melissa, Nguyen, Tung, Land, Susan J., Ruden, Douglas M., Lu, Xiangyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Research Foundation 2012
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304048/
https://ncbi.nlm.nih.gov/pubmed/22435069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00035
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