Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift

This paper describes a new program SnpSift for filtering differential DNA sequence variants between two or more experimental genomes after genotoxic chemical exposure. Here, we illustrate how SnpSift can be used to identify candidate phenotype-relevant variants including single nucleotide polymorphi...

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Bibliografiska uppgifter
Huvudupphovsmän: Cingolani, Pablo, Patel, Viral M., Coon, Melissa, Nguyen, Tung, Land, Susan J., Ruden, Douglas M., Lu, Xiangyi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Research Foundation 2012
Ämnen:
Genetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304048/
https://ncbi.nlm.nih.gov/pubmed/22435069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00035
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