Using Drosophila melanogaster as a Model for Genotoxic Chemical Mutational Studies with a New Program, SnpSift

This paper describes a new program SnpSift for filtering differential DNA sequence variants between two or more experimental genomes after genotoxic chemical exposure. Here, we illustrate how SnpSift can be used to identify candidate phenotype-relevant variants including single nucleotide polymorphi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cingolani, Pablo, Patel, Viral M., Coon, Melissa, Nguyen, Tung, Land, Susan J., Ruden, Douglas M., Lu, Xiangyi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Research Foundation 2012
Gaiak:
Genetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304048/
https://ncbi.nlm.nih.gov/pubmed/22435069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00035
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