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Landscape of EGFR Signaling Network in Human Cancers: Biology and Therapeutic Response in Relation to Receptor Subcellular Locations

The epidermal growth factor receptor (EGFR) pathway is one of the most dysregulated molecular pathways in human cancers. Despite its well-established importance in tumor growth, progression and drug-resistant phenotype over the past several decades, targeted therapy designed to circumvent EGFR has y...

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Detalhes bibliográficos
Main Authors: Han, Woody, Lo, Hui-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304012/
https://ncbi.nlm.nih.gov/pubmed/22261334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.01.011
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