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AMMONIA INCREASES PARACELLULAR PERMEABILITY OF RAT BRAIN ENDOTHELIAL CELLS BY A MECHANISM ENCOMPASSING OXIDATIVE/NITROSATIVE STRESS AND ACTIVATION OF MATRIX METALLOPROTEINASES
Ammonia is responsible for cerebral edema (CE) associated with acute liver failure (ALF), but the role of the vasogenic mechanism has been a matter of dispute. Here, we tested the hypothesis that ammonia induces changes in blood-brain barrier (BBB) permeability by a mechanism coupled to oxidative/ n...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303972/ https://ncbi.nlm.nih.gov/pubmed/22260250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07669.x |
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