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Requirement of TrkB for synapse elimination in developing cerebellar Purkinje cells

The receptor tyrosine kinase TrkB and its ligands, brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5), are critically important for growth, survival and activity-dependent synaptic strengthening in the central nervous system. These TrkB-mediated actions occur in a highly cell-typ...

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Autors principals: Bosman, Laurens W. J., Hartmann, Jana, Barski, Jaroslaw J., Lepier, Alexandra, Noll-Hussong, Michael, Reichardt, Louis F., Konnerth, Arthur
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303929/
https://ncbi.nlm.nih.gov/pubmed/17940915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11068-006-9002-z
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