Cap-Gly Proteins at Microtubule Plus Ends: Is EB1 Detyrosination Involved?

Localization of CAP-Gly proteins such as CLIP170 at microtubule+ends results from their dual interaction with α-tubulin and EB1 through their C-terminal amino acids −EEY. Detyrosination (cleavage of the terminal tyrosine) of α-tubulin by tubulin-carboxypeptidase abolishes CLIP170 binding. Can detyro...

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Autores principales: Bosson, Anouk, Soleilhac, Jean-Marc, Valiron, Odile, Job, Didier, Andrieux, Annie, Moutin, Marie-Jo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303835/
https://ncbi.nlm.nih.gov/pubmed/22432029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033490
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