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ER Stress in Retinal Degeneration in S334ter Rho Rats
The S334ter rhodopsin (Rho) rat (line 4) bears the rhodopsin gene with an early termination codon at residue 334 that is a model for several such mutations found in human patients with autosomal dominant retinitis pigmentosa (ADRP). The Unfolded Protein Response (UPR) is implicated in the pathophysi...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303830/ https://ncbi.nlm.nih.gov/pubmed/22432009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033266 |
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