ER Stress in Retinal Degeneration in S334ter Rho Rats

The S334ter rhodopsin (Rho) rat (line 4) bears the rhodopsin gene with an early termination codon at residue 334 that is a model for several such mutations found in human patients with autosomal dominant retinitis pigmentosa (ADRP). The Unfolded Protein Response (UPR) is implicated in the pathophysi...

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Bibliographic Details
Main Authors: Shinde, Vishal M., Sizova, Olga S., Lin, Jonathan H., LaVail, Matthew M., Gorbatyuk, Marina S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303830/
https://ncbi.nlm.nih.gov/pubmed/22432009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033266
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