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Features of Methylation and Gene Expression in the Promoter-Associated CpG Islands Using Human Methylome Data

CpG islands are typically located in the 5′ end of genes and considered as gene markers because they play important roles in gene regulation via epigenetic change. In this study, we compared the features of CpG islands identified by several major algorithms by setting the parameter cutoff values in...

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Detalhes bibliográficos
Main Authors: Du, Xin, Han, Leng, Guo, An-Yuan, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303704/
https://ncbi.nlm.nih.gov/pubmed/22474411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/598987
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