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Manipulation of the Complement System for Benefit in Sepsis

There is evidence in sepsis, both in rodents and in humans, that activation of the complement system results in excessive production of C5a, which triggers a series of events leading to septic shock, multiorgan failure, and lethality. In rodents following cecal ligation and puncture (CLP), which ind...

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Autors principals: Ward, Peter A., Guo, Ren-Feng, Riedemann, Niels C.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303540/
https://ncbi.nlm.nih.gov/pubmed/22482043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/427607
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