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Manipulation of the Complement System for Benefit in Sepsis

There is evidence in sepsis, both in rodents and in humans, that activation of the complement system results in excessive production of C5a, which triggers a series of events leading to septic shock, multiorgan failure, and lethality. In rodents following cecal ligation and puncture (CLP), which ind...

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Bibliografiske detaljer
Main Authors: Ward, Peter A., Guo, Ren-Feng, Riedemann, Niels C.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303540/
https://ncbi.nlm.nih.gov/pubmed/22482043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/427607
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