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Pyrvinium, A Potent Small Molecule WNT Inhibitor, Increases Engraftment And Inhibits Lineage Commitment Of Mesenchymal Stem Cells (MSCs)
We and others have found that Wnt signaling inhibition is important in mesenchymal stem cell (MSC) self-renewal. Pyrvinium was identified as a potent Wnt inhibitor in a chemical screen for small molecules. In the present study we hypothesized that pyrvinium will enhance MSC self-renewal to improve t...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303160/ https://ncbi.nlm.nih.gov/pubmed/22332749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2012.00767.x |
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