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sFRP2 Suppression of Bone Morphogenic Protein (BMP) and Wnt Signaling Mediates Mesenchymal Stem Cell (MSC) Self-renewal Promoting Engraftment and Myocardial Repair

Transplantation of mesenchymal stem cells (MSCs) is a promising therapy for ischemic injury; however, inadequate survival of implanted cells in host tissue is a substantial impediment in the progress of cellular therapy. Secreted Frizzled-related protein 2 (sFRP2) has recently been highlighted as a...

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Bibliografiska uppgifter
Huvudupphovsmän: Alfaro, Maria P., Vincent, Alicia, Saraswati, Sarika, Thorne, Curtis A., Hong, Charles C., Lee, Ethan, Young, Pampee P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975189/
https://ncbi.nlm.nih.gov/pubmed/20826809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135335
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