Loss and Recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation Is a Mechanism Involved in Epithelial-Mesenchymal-Epithelial Transitions

BACKGROUND: N-acetylglucosaminyltransferase-III (GnT-III) is a glycosyltransferase encoded by Mgat3 that catalyzes the addition of β1,4-bisecting-N-acetylglucosamine on N-glycans. GnT-III has been pointed as a metastases suppressor having varying effects on cell adhesion and migration. We have previ...

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Detalhes bibliográficos
Main Authors: Pinho, Salomé S., Oliveira, Patrícia, Cabral, Joana, Carvalho, Sandra, Huntsman, David, Gärtner, Fátima, Seruca, Raquel, Reis, Celso A., Oliveira, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302839/
https://ncbi.nlm.nih.gov/pubmed/22427986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033191
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