PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data

Crosslinking and immunoprecipitation (CLIP) protocols have made it possible to identify transcriptome-wide RNA-protein interaction sites. In particular, PAR-CLIP utilizes a photoactivatable nucleoside for more efficient crosslinking. We present an approach, centered on the novel PARalyzer tool, for...

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Detalhes bibliográficos
Main Authors: Corcoran, David L, Georgiev, Stoyan, Mukherjee, Neelanjan, Gottwein, Eva, Skalsky, Rebecca L, Keene, Jack D, Ohler, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302668/
https://ncbi.nlm.nih.gov/pubmed/21851591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-8-r79
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