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The solution structure of the intramolecular photoproduct of d(TpA) derived with the use of NMR and a combination of distance geometry and molecular dynamics.

One and two dimensional NMR techniques have been used together with molecular modelling to obtain the solution structure for the photoproduct d(TpA)*. The NMR data confirm that the cyclobutane linkage is formed between the bonds thymine C6-C5 and adenine C5-C6. The 2D NOE data are used as constraint...

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Publicat a:Nucleic Acids Res
Autors principals: Koning, T M, Davies, R J, Kaptein, R
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1990
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2326164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.2.277
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