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The Dewar photoproduct of thymidylyl(3′→5′)- thymidine (Dewar product) exhibits mutagenic behavior in accordance with the “A rule”

In contrast to the highly mutagenic pyrimidine(6–4)pyrimidone photoproduct, its Dewar valence isomer (Dewar product) has low mutagenic potential and produces a broad range of mutations [LeClerc, J. E., Borden, A. & Lawrence, C. W. (1991) Proc. Natl. Acad. Sci. USA 88, 9685–9689]. To determine the or...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Lee, Joon-Hwa, Bae, Sung-Hun, Choi, Byong-Seok
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18277/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10758155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.080057097
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