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The Dewar photoproduct of thymidylyl(3′→5′)- thymidine (Dewar product) exhibits mutagenic behavior in accordance with the “A rule”

In contrast to the highly mutagenic pyrimidine(6–4)pyrimidone photoproduct, its Dewar valence isomer (Dewar product) has low mutagenic potential and produces a broad range of mutations [LeClerc, J. E., Borden, A. & Lawrence, C. W. (1991) Proc. Natl. Acad. Sci. USA 88, 9685–9689]. To determine the or...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lee, Joon-Hwa, Bae, Sung-Hun, Choi, Byong-Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18277/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10758155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.080057097
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