HLA B*5701-Positive Long-Term Nonprogressors/Elite Controllers Are Not Distinguished from Progressors by the Clonal Composition of HIV-Specific CD8(+) T Cells

To better understand the qualitative features of effective human immunodeficiency virus (HIV)-specific immunity, we examined the TCR clonal composition of CD8(+) T cells recognizing conserved HIV p24-derived epitopes in HLA-B*5701-positive long-term nonprogressors/elite controllers (LTNP/EC) and HLA...

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Hlavní autoři: Mendoza, Daniel, Royce, Cassandra, Ruff, Laura E., Ambrozak, David R., Quigley, Máire F., Dang, Thurston, Venturi, Vanessa, Price, David A., Douek, Daniel C., Migueles, Stephen A., Connors, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302536/
https://ncbi.nlm.nih.gov/pubmed/22278241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06982-11
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