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Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus Inhibits the Antiviral Function of Interferon-Stimulated Gene 15

Type I interferon (alpha/beta interferon [IFN-α/β]) stimulates the expression of interferon-stimulated gene 15 (ISG15), which encodes a ubiquitin-like protein, ISG15. Free ISG15 and ISG15 conjugates function in diverse cellular pathways, particularly regulation of antiviral innate immune responses....

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Detalhes bibliográficos
Main Authors: Sun, Zhi, Li, Yanhua, Ransburgh, Russell, Snijder, Eric J., Fang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302520/
https://ncbi.nlm.nih.gov/pubmed/22258253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06466-11
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